杜桂珍

发布者:卫生毒理学系发布时间:2017-07-18浏览次数:3815


杜桂珍,博士主要研究领域为环境危险因素与人类生殖健康,重点研究环境化学物的内分泌干扰效应、环境化学物的不良生殖结局、环境化学物对早期胚胎发育的影响及作用机制。20142月至20161月,在美国加州大学洛杉矶分校人类遗传学系开展科研,担任项目助理研究员一职。近年来主持国家自然科学基金面上项目、青年项目、省自然科学基金面上项目等。


研究方向:环境与生殖发育健康

  

联系方式:

邮箱:guizhendu@njmu.edu.cn

电话:025-86868426

  

近五年代表性论文:

1.     Zhang R, Guo J, Wang Y, Sun R, Dong G, Wang X, Du G*. Prenatal bisphenol S exposure induces hepatic lipid deposition in male mice offspring through downregulation of adipose-derived exosomal miR-29a-3p. J Hazard Mater. 2023. 453:131410.

2.     Wu X, Li S, Ni Y, Qi C, Bai S, Xu Q, Fan Y, Ma X, Lu C, Du G*, Xu Z*, Qin Y*. Maternal BPAF exposure impaired synaptic development and caused behavior abnormality in offspring. Ecotoxicol Environ Saf. 2023. 256:114859.

3.     Wu X, Li S, Zhang M, Bai S, Ni Y, Xu Q, Fan Y, Lu C, Xu Z, Ji C, Du G*, Qin Y*. Early-life bisphenol AP exposure impacted neurobehaviors in adulthood through microglial activation in mice. Chemosphere. 2023. 317:137935.

4.     Dong G, Sun R, Zhang R, Qin Y, Lu C, Wang X, Xia Y*, Du G*. Preimplantation triclosan exposure alters uterine receptivity through affecting tight junction protein. Biol Reprod. 2022. 107(1):349-357.

5.     Dong G, Zhang R, Hu Q, Martin EM, Qin Y, Lu C, Xia Y, Wang X, Du G*. Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells. Arch Toxicol. 2022. 96(2):559-570.

6.     Dong G, Zhang R, Huang H, Lu C, Xia Y, Wang X, Du G*. Exploration of the developmental toxicity of TCS and PFOS to zebrafish embryos by whole-genome gene expression analyses. Environ Sci Pollut Res Int. 2021. 28(40): 56032-56042.

7.     Huang Z, Yu H, Du G (co-first author), Han L, Huang X, Wu D, Han X, Xia Y, Wang X, Lu C. Enhancer RNA lnc-CES1-1 inhibits decidual cell migration by interacting with RNA-binding protein FUS and activating PPARγ in URPL. Mol Ther Nucleic Acids. 2021. 24:104-112.

8.     Du G, Yu M, Xu Q, Huang Z, Huang X, Han L, Fan Y, Zhang Y, Wang R, Xu S, Han X, Fu G, Lv S, Qin Y, Wang X, Lu C, Xia Y. Hypomethylation of PRDM1 is associated with recurrent pregnancy loss. J Cell Mol Med. 2020. 24(12): 7072-7077.

9.     Du G*, Hu J, Huang Z, Yu M, Lu C, Wang X, Wu D. Neonatal and juvenile exposure to perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS): advance puberty onset and kisspeptin system disturbance in female rats. Ecotoxicology and Environmental Safety. 2019. 167:412-421.

10.   Shi Q, Zhuang Y, Hu T, Lu C, Wang X, Huang H, Du G*. Developmental toxicity of triclocarban in zebrafish (Danio rerio) embryos. J Biochem Mol Toxicol. 2019. e22289.


 


 




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